49ers Injury Report: Christian McCaffrey, Deebo Samuel and Trent Williams

Christian McCaffrey - SIC score 79

Ruled out with oblique injury - returned to the game for one run in second half but then went to locker room and ruled out - concerning for his availability next Monday against Vikings - not long term but will bother him in the short term

It was not immediately clear when McCaffrey picked up the injury, but he appeared to get twisted on a rush in the third quarter.

He grabbed at his oblique on the Brock Purdy pick the next play.

Deebo Samuel - SIC score 72

Ruled out with a right shoulder injury - possibly injured in the middle of the first quarter when he landed hard on a rush attempt - video didn't show clear injury mechanism

Trent Williams - SIC score 70

By video, likely right high ankle sprain with possibility of MCL sprain - returned to the game but had limited effectiveness and 49ers had to chip on his side - missed 3 games last year but avoided IR