NFL Week 6 TNF Preview: 49ers vs. Seahawks | Injury Report & Free Pick

49ers vs. Seahawks Thursday Night Football Game Overview

Thursday Night Football in Week 6 presents a pivotal NFC West showdown as the San Francisco 49ers travel to face the Seattle Seahawks.

 The 49ers, sitting at 2-3 and winless in the division, are under pressure to turn their season around after a rough start. Meanwhile, the Seahawks, with playoff aspirations of their own, will look to capitalize on home-field advantage to gain a crucial division victory. 

Injuries and key matchups will play a significant role, as both teams fight for the valuable division win. Listed below are key injury insights for each team.

San Francisco 49ers - SIC Health Score 82.4

San Francisco 49ers Key Injury Insights

Javon Hargrave DT

Suffered a partial triceps tear Sunday and now is likely out for the rest of the season as the injury will require surgery, limiting the depth of the 49ers defensive line

Dre Greenlaw LB

Unfortunately, he suffered a torn Achilles during the Super Bowl on February 11, 2024. Although there was hope for him to be ready for the season, he is currently on the PUP list and may need to miss at least the first four games of the season.

Demetrius Flannigan-Fowles LB

Missed Week 5 with a calf injury and on a short week will miss TNF vs the Seahawks. 

Talanoa Hufanga S

Hufanga suffered torn ligaments in his wrist during the Week 5 game and will be out at least a month.

Ji'Ayir Brown S

Brown was limited in practice on Tuesday due to an ankle injury but is expected to play Week 6 versus the Seahawks.
 

Seattle Seahawks - SIC Health Score 87.4

Seattle Seahawks Key Injury Insights

Uchenna Nwosu LB 

Exited Sunday's game early with a thigh injury and did not return, with their next game being TNF against the 49ers, he has been ruled out, he previously missed Weeks 1-4 with a knee injury.

Boye Mafe LB

Mafe was a full participant in practice on Tuesday and Wednesday heading into Week 6 after missing the past two games with a knee injury.

Check back for more updates closer to game time.

Matchup Breakdown: Position Groups Impacted by Injuries

Check out the 49ers vs. Seahawks SIC Health Scores and Field View here with SIC Data - from less than $1 a week on the annual plan for a limited time!

Injury-Related Betting Insights & Free Pick

Kenneth Walker III is another week healthier from an oblique injury and we expect him to take advantage of the health mismatch between the Seahawks Run Offense (89.9 SIC health score rating) compared to the 49ers Run Defense (66.3 SIC health score rating)

Free SIC Pick: Kenneth Walker III Over 58.5 Rushing Yards (-110 at bet365)

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SIC PICKS ARE INSIDER INJURY KNOWLEDGE FROM FORMER PRO SPORTS TEAM DOCTORS TO GIVE YOU A WINNING EDGE IN SPORTS BETTING!

SIC PICKS are powered by the proven SIC Score algorithms from our exclusive panel of former Pro Sports Team doctors to give you a sports betting edge. Each day our team of doctors analyze the players and teams and share their expert insights to help you make informed bets on the biggest unknown to sportsbooks and sports bettors - player health and injuries!